Researchers Identify Drug Target for ATRA – BIDMC

Avatar Mice – Boston Globe
September 21, 2014
Evolutionary Genome Relic – BIDMC
February 4, 2015
Show all

Researchers Identify Drug Target for ATRA, the First Precision Cancer Therapy

Discovery offers a new way to fight cancer by targeting the Pin1 enzyme

BOSTON – Targeted cancer therapies work by blocking a single oncogenic pathway to halt tumor growth. But because cancerous tumors have the unique ability to activate alternative pathways, they are often able to evade these therapies — and regrow. Moreover, tumors contain a small portion of cancer stem cells that are believed to be responsible for tumor initiation, metastasis and drug resistance. Thus, eradicating cancer stem cells may be critical for achieving long-lasting remission, but there are no drugs available that specifically attack cancer stem cells.

Read the full article on the Beth Israel Deaconess Medical Center Website:

Source URL: https://www.bidmc.org/about-bidmc/news/researchers-identify-drug-target-for-atra-the-first-precision-cancer-therapy

Leave a Reply